Written By. Callum Hedman, March 4, 2026 What is the Endocannabinoid System (ECS)? The Endocannabinoid system (ECS) is a complex cell-signaling system found in virtually all vertebrates and many invertebrates, discovered in the early 1990s while researchers were studying how cannabis interacts with the body. Insects are the only major known exception, as they lack […]